PREPRINTS

Identification of extracellular membrane protein ENPP3 as a major cGAMP hydrolase, cementing cGAMP's role as an immunotransmitter
Rachel Mardjuki, Songnan Wang, Jacqueline Carozza, Gita Abhiraman, Xuchao Lyu, Lingyin Li
bioRxiv 2024.01.12.575449

Blocking oligomerization is the most viable strategy to inhibit STING
Rebecca Chan, Xujun Cao, Sabrina L. Ergun, Evert Njomen, Stephen R. Lynch, Benjamin F. Cravatt, Lingyin Li
bioRxiv 2023.08.11.553045


STING activation of IRF3 is tuned by PELI2 to suppress basal activation and reinforce the anti-viral response
Christopher Ritchie, Lingyin Li
bioRxiv 2023.04.15.537029


A cGAMP-containing hydrogel for prolonged SARS-CoV-2 RBD subunit vaccine exposure induces a broad and potent humoral response
Emily C. Gale, Lauren J. Lahey, Volker Böhnert, Abigail E. Powell, Ben S. Ou, Jacqueline A. Carozza, Lingyin Li, Eric A. Appel
bioRxiv 2021.07.03.451025